Selected engineered systems have been composed of phage-encoded cis regulatory elements, such as phage origins of DNA replication or phage promoters that drive abortive or suicide systems in the ...

In addition, we verified that overexpression of pA151R facilitated DNA virus Herpes simplex virus 1 (HSV-1) replication by inhibiting IFN ... we co-transfected IFN-β promoter containing the ...

Thus, magnesium plays a crucial role in the DNA replication process and preservation ... 11β-hydroxysteroid dehydrogenase-2 (Hsd11b2) promoters, which affect the metabolism of neonatal offspring.

Participants DNA samples from 36 individuals with normal uric acid ... Our study is the first to identify one SNP in the promoter region (c.-46G>A) and three non-coding variants (c.506+32T>C, ...

DNA transcription is the vital first step needed for switching on our genes. For a gene to be switched on, it must be acted ...

DNA (deoxyribonucleic acid), the molecular "blueprint" carrying the genetic instructions that influence the growth, ...

How cells respond to mitochondrial DNA (mtDNA) damage is not fully understood. This study uncovers a mechanism of mtDNA ...

A team has unearthed new findings about what happens during the minutes and hours after a cell divides, expanding our understanding of human biology -- and potentially leading to better medicines.

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means ...

Comparison of that ancient DNA with modern human DNA showed that the two species had interbred and that people today still carry the genetic fingerprint of that intermixing. Since then ...

The PIF/Harbinger-derived ADF-IL protein recruits KAT2B to drive its nuclear translocation and local chromatin acetylation, ...