This important manuscript proposes a new strategy for the identification of new mechanisms of drug resistance based on SAturated Transposon Analysis in Yeast (SATAY), a powerful transposon sequencing ...

zahav.net.il Methods Six new patients from four separate families, with clinical and biochemical diagnosis of ATP synthase deficiency, were studied. TMEM70 sequence analysis of the three exons and ...

In addition to the tightly coupled synaptic relationship between neuronal synapses and astrocytes, astrocyte-to-astrocyte transmission through gap junctions, as well as paracrine release of ATP ...

In this Review, we summarise common mechanisms driving acute and long-term side-effects and discuss monitoring strategies for radiotherapy survivors. We explore ways to mitigate toxic effects through ...

The top four men’s players in the world will keep their ranking positions after the Australian Open, but there will be some big climbs and drops further down the ATP Rankings. The final in Melbourne ...

Department of Chemistry and Biochemistry, University of California Santa Barbara, Santa Barbara, California 93106, United States Biomolecular Science and Engineering Program, University of California ...

"These findings illuminate a critical mechanism that connects local synaptic activity to the broader gene expression changes necessary for learning and memory," said Mark Dell'Acqua, professor of ...

To use Windows Defender ATP (Advanced Threat Protection), onboard your devices to the platform using Configuration Manager, Microsoft Intune, or manual installation. Access the Microsoft Defender ...

The data are generally solid as the authors deploy multiple, orthogonal readouts and methods for manipulating reactive oxygen species and ATP. The work will be of interest to those studying antibiotic ...

PMX and its polyglutamated derivatives inhibit thymidylate synthase (TYMS), dihydrofolate reductase (DHFR ... Genes related to antifolate resistance include DHFR, TYMS, ATP-binding cassette subfamily ...